Topic: metabolite signaling

Metabolism actively interacts with the proteome, transcriptome, and genome, thereby influencing all facets of biological information and providing cells the adaptability required for optimal functioning across time and space. Neurodevelopment, in particular, depends on the timely integration of numerous molecular signals across cell types, thus deeply relying on metabolite signaling functions. Although measuring changes in metabolites is useful to describe the association between molecules and disorders, the molecular mechanisms through which these metabolites affect neurodevelopment remain un