Topic: microglial senescence

Aging is a significant risk factor for the development of neurodegenerative disease like Alzheimer’s disease (AD) and Parkinson’s disease. Microglia, as important immune cells in the brain, play a crucial role in maintaining brain homeostasis, particularly related to iron storage and metabolism. Investigating the role of microglia in aging can provide insights into disease identification and potential therapies. Despite being long-lived immune cells, microglia have been understudied in the context of aging. Their heterogeneity and functions have not been fully explored, which is important give