Astroglial control of prefrontal dopamine tone shapes behavior
Juliette Royer, Olga Chaikovska, Xia Li, Wenli Niu, Sambre Mach, Paola Bezzi, Micaela Galante, Glenn Dallerac · FENS Forum 2024
Brain cognitive performances are typically thought to fully rely on neurons. Yet, recent research has shown that the other major cell type of the brain, the astrocyte, actively influence information processing. Astrocytes are indeed involved in the modulation of neuronal circuit activities underlying behavior, by regulating extracellular concentrations of ion and neurotransmitters. We have previously found that astrocytes control dopamine levels in the prefrontal cortex, thereby modulating synaptic transmission and plasticity. Dopamine release can occur physically, responding to specific stimu
ePoster · Neuroscience