Topic: miR-204-5p

MicroRNAs, small non-coding RNAs that regulate gene expression post-transcriptionally, have been shown to be deregulated in the development of Alzheimer's disease (AD), the major cause of dementia in the elderly. Nowadays implies a large health, social and economic burden with no effective disease-modifying therapy available. A deeper understanding of the events involved in early synaptic dysfunction in AD would provide the necessary insight to eventually identify new targets and develop novel therapeutic strategies.Transcriptomic analyses revealed that a factor involved in these deficits is t