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Topic: Modularization

Seminar
1 seminar

In Applied Mathematics and Biology

Seminar · Computational Neuroscience

Self-organized formation of discrete grid cell modules from smooth gradients

Sarthak Chandra · Fiete lab, MIT

Wed, Nov 3, 2021 · 17:35 UTC

Modular structures in myriad forms — genetic, structural, functional — are ubiquitous in the brain. While modularization may be shaped by genetic instruction or extensive learning, the mechanisms of module emergence are poorly understood. Here, we explore complementary mechanisms in the form of bottom-up dynamics that push systems spontaneously toward modularization. As a paradigmatic example of modularity in the brain, we focus on the grid cell system. Grid cells of the mammalian medial entorhinal cortex (mEC) exhibit periodic lattice-like tuning curves in their encoding of space as animals n