Exposure to a high-fat diet during adolescence affects the mu opioid receptor gene expression in the lateral septum of adult rats
Victoria Velásquez, Ramón Sotomayor-Zárate · FENS Forum 2024
Obesity is a multifactorial disease, where the major factor involved is the consumption of high-fat, high-palatability food. The prevalence of this disease has increased in all age groups, but the increase in children and youth is alarming. Food intake is controlled by brain areas involved in homeostatic and hedonic control, both systems being regulated by the GABAergic nucleus, lateral septum (LS). The LS neurons are regulated by several membrane receptors, where the regulation of food intake in an obese condition by μ-opioid receptor (MOR) has not been previously studied.This work aimed to e
ePoster · Neuroscience