Skip to contentSkip to filters

We use cookies for analytics.

Topic: morphology reduction

ePoster
1 ePoster

In Biology and Biophysics

ePoster · Computational Neuroscience

DendroTweaks: An interactive approach for unraveling dendritic dynamics

Roman Makarov, Spyridon Chavlis, Panayiota Poirazi · FENS Forum 2024

Neurons rely on the interplay between dendritic morphology and ion channels to transform synaptic inputs into a sequence of somatic spikes. Detailed biophysical models with active dendrites have been instrumental for exploring this interaction. However, such models can be challenging to understand and validate due to the large number of parameters involved. In this work, we introduce DendroTweaks — a framework designed to illuminate how morpho-electric properties map to dendritic events, and how these dendritic events shape neuronal output. Through its graphical interface, users can access the