Consecutive training on different movement sequences performed with the same motor effectors often leads to retroactive interference - obstructing memory for the initially trained sequence but not for the second. However, in the context of hippocampal-system dependent memories, a poor learning experience, one whose behavioral effects would soon decay, can be enhanced if temporally paired with a ‘strong’, consolidation-triggering, experience. The Synaptic Tagging and Capture hypothesis (STC) explains this paradoxical enhancement by suggesting that synapses specifically engaged in a ‘weak’ learn
ePoster · Neuroscience