Topic: motor-related prefrontal areas

Previous research based on rodent models suggested that motor-related prefrontal areas mediate diverse functions including motor planning and cognitive functions such as decision-making, and also their flexible expression. However, whether neurons in these areas that mediate such functions are segregated populations or largely the same population are not clear. To address this question, in this study, we trained mice to perform distinct cognitive and motor task under head fixation while layer 2/3 (L2/3) neurons in the target area are imaged under multi-photon microscopy. In the cognitive task,