The role of lifetime physical activity on Parkinson’s symptoms severity - Revenge of the couch potato?
Elena Guerra, Adrian Asendorf, Magdalena Banwinkler, Verena Dzialas, Alicia Jones, Hendrik Theis, Thilo van Eimeren, Merle Hönig · FENS Forum 2024
Lifestyle factors like lifetime physical activity (LPA) may support motor reserve in Parkinson’s disease (PD), hence the capability to compensate for the effect of dopamine transporter (DaT) loss on motor function. In 20 de novo PD patients, we investigated the potential protective role of LPA on motor function and associated network connectivity by means of resting-state functional magnetic resonance imaging (rs-fMRI). In this group, putaminal DaT integrity was assessed by standardized uptake value ratio (SUVR) for the putamen derived from DaT SPECT imaging. Motor symptom severity was measur
ePoster · Neuroscience