ePoster · Neuroscience
Use-dependent plasticity of cortical proprioceptive representation in mice
Fei Ma, Ignacio Alonso, Mario Prsa · FENS Forum 2024
Proprioception enables an organism to sense the position and motion of its limbs and body in space. Comparative evolutionary studies have proposed that the organization of the proprioceptive cortex does not emerge as a consequence of innervation density but rather as a result of the actual use of a limb. We tested this hypothesis by quantifying if and how the proprioceptive cortical representation reorganizes after skilled motor training in adult mice as well as enriched environmental exposure during development.We performed wide-filed calcium imaging of cortical activation in response to mult