Topic: MPC

The balance between the quiescent and activated states of adult neural stem/progenitor cells (NSPCs) is crucial for maintaining sustained neurogenesis throughout life. NSPCs mostly remain quiescent during adulthood but can proliferate in response to specific stimuli. While cellular metabolism has emerged as a key factor in determining the activity state of stem cells, its precise role in orchestrating the transition from quiescence to proliferation in NSPCs is not fully understood. Generally, stem cells rely on glycolytic metabolism to support the synthesis of cellular building blocks necessar