Unraveling the mechanisms underlying corticosterone-induced impairment in novel object recognition in mice
Julia Welte, Urszula Skupio, Roman Serrat, Francisca Julio-Kalajzić, Doriane Gisquet, Astrid Cannich, Luigi Bellocchio, Francis Chaouloff, Giovanni Marsicano, Sandrine Pouvreau · FENS Forum 2024
Stress-induced alterations in cognitive functions are documented to be mediated by corticosteroid hormones and hence mineralocorticoid (MR) and/or glucocorticoid receptor (GR) activation. Moreover, recent evidence underscores the pivotal role of the endocannabinoid system (ECS) as a modulator of stress responses including the impact of corticosteroids on diverse memory processes. However, the precise mechanisms governing corticosteroid-induced impairment of novel object recognition (NOR) retrieval are yet unknown. The present study aims at elucidating the intricate interactions between cortico
ePoster · Neuroscience