Towards using small topologically constrained networks in-vitro in combination with in-silico models
Stephan Ihle,Sean Weaver,Katarina Vulić,János Vörös,Sophie Girardin,Thomas Felder,Julian Hengsteler,Jens Duru,Csaba Forró,Tobias Ruff,Benedikt Maurer · COSYNE 2022
Understanding how the brain can store and process information is one of the biggest challenges we are currently facing in the field of neuroscience. It is possible to study the brain as a whole. However, such approaches tend to only recover neural activity from a sparse subset. To counteract this problem, we are using a bottom-up neuroscience paradigm, where neurons are cultured on top of a multi-electrode array (MEA). The MEA can be used to stimulate and record neural activity. To further reduce the complexity, we culture neurons inside of a polydimethylsiloxane (PDMS) microstructure, which e
Sat, Mar 19, 2022