Overcoming non-identifiability issues in brain-wide communication models
Belle Liu, Jacob Sacks, Matthew Golub · COSYNE 2025
Advancements in large-scale neural recordings are now enabling opportunities to probe cognitive computations across simultaneously recorded brain regions, necessitating modeling tools for deciphering multi-region interactions. In an emerging class of dynamical models, brain-wide neural activity is reconstructed by region-specific modules that interact through communication channels and may receive additional information as inputs. These models aim to recover the effective connectome, which includes the inter-region connection diagram and the messages communicated between regions. However, with
ePoster · Neuroscience