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Topic: multi-region interactions

ePoster
1 ePoster

In Neuroscience

Overcoming non-identifiability issues in brain-wide communication models

Belle Liu, Jacob Sacks, Matthew Golub · COSYNE 2025

Advancements in large-scale neural recordings are now enabling opportunities to probe cognitive computations across simultaneously recorded brain regions, necessitating modeling tools for deciphering multi-region interactions. In an emerging class of dynamical models, brain-wide neural activity is reconstructed by region-specific modules that interact through communication channels and may receive additional information as inputs. These models aim to recover the effective connectome, which includes the inter-region connection diagram and the messages communicated between regions. However, with

ePoster · Neuroscience