Deciphering brain function through in vivo simultaneous multi-region neuronal level brain imaging of freely behaving animals
Tina Mahmoudi, Yeseul Lee, Roshni Christo, Jalani Kanem, Cristian Santos, Alexander Papanicolaou, Yasaman Soudagar · FENS Forum 2024
To understand circuit mechanisms underlying naturalistic behavior, it is essential to simultaneously record neural activity in multiple brain regions and correlate it with behavior. We report a multi-region miniscope that uses four highly flexible and light-weight imaging fiber bundles (IFB) and enables imaging of up to 4 brain areas in freely behaving subjects. Transgenic animals or virus expression is used to express a cell-type specific green fluorescence tag. Up to four GRIN Lens-Connectors (GLCs) can be surgically implanted into the brain regions of interest. The GLCs are designed with th
ePoster · Neuroscience