Topic: multichannel silicon probes

High-throughput electrophysiological recordings, using multichannel silicon probes, allow simultaneous registration of neural activity from multiple brain regions. However, the difficulty of determining the precise localisation of recording sites within neural subcompartments creates challenges for data analysis and the interpretation of experimental results. While electrode localisation can be achieved to some extent by post-mortem histological reconstruction of the probes, it can be improved by real-time discrimination of the electrophysiological features of the signal: evoked potentials tri