Relation of topological patterns of brain network with cognitive phenotypes identified by robotic assessment in patients with temporal lobe epilepsy
Karla Batista Garcia-Ramo, Theodore Aliyianis, Brooke Beattie, Adam Falah, Spencer Finn, Lysa Boissé-Lomax, Garima Shukla, Andrea Ellsay, Jason Gallivan, Stephen H Scott, Gavin P Winston · FENS Forum 2024
To identify patterns of structural networks associated with cognitive phenotypes detected with robotic technology in patients with temporal lobe epilepsy (TLE). Network analysis was performed using multimodal MRI from TLE patients (n=22) and healthy subjects (n=20). Five tests with the Kinarm robot were used to evaluate five cognitive domains. Four graph theory metrics were computed to characterize structural networks. Structural and cognitive phenotypes were identified using an unsupervised learning algorithm, and the association between them evaluated. Three cognitive clusters were identifie
ePoster · Neuroscience