Decoding of fMRI resting-state using task-based MVPA supports the Incentive-Sensitization Theory in smokers
Cindy Lor, David Steyrl, Mengfan Zhang, Feng Zhou, Benjamin Becker, Marcus Herdener, Boris B. Quednow, Amelie Haugg, Frank Scharnowski · FENS Forum 2024
Background The Incentive-Sensitization Theory postulates that addiction is primarily driven by the sensitization of the brain’s reward system to addictive substances, such as nicotine. According to this theory, exposure to such substances leads to an increase in ‘wanting’, while ‘liking’ the experience remains relatively unchanged. Although this candidate mechanism has been well substantiated through animal brain research, its translational validity for humans has only been partially demonstrated so far, with evidence from human neuroscience data being very limited.Methods From fMRI data of N=
ePoster · Neuroscience