Cognitive performance is enhanced by aerobic-strength training, and related to physical fitness and reduced platinum levels in testicular germ cell cancer survivors
Barbara Ukropcova, Ali Amiri, Lucia Slobodova, Karin Marcek Malenovska, Katarina Rerkova, Martin Schon, Zuzana Novakova, Viktor Oliva, Viera Litvakova, Milan Sedliak, Martin Krssak, Tomas Pluhacek, Michal Mego, Michal Chovanec, Jozef Ukropec · FENS Forum 2024
Platinum-based chemotherapy can accelerate cognitive and metabolic decline in cancer survivors. Physical exercise has a potential to reduce chemotherapy-related toxicity. Our aim was to assess the effects of aerobic-strength training on cognitive functions, physical fitness and metabolism in testicular germ cell tumour (TGCT) survivors, treated with platinum-based chemotherapy. TGCT survivors were enrolled in a 6-month intervention (supervised aerobic-strength training / controls n=20 / 8, age 42.1±7.6 yrs, BMI:27.7±3.8 kg/m², VO2max:29.2±6.7 mlO2/kg/min, 1-20 years post-treatment). Abdominal
ePoster · Neuroscience