Sex-dependent effects of voluntary physical exercise on object recognition memory restoration after traumatic brain injury in middle-aged rats
David Costa, Meritxell Torras-Garcia, Odette Estrella, Isabel Portell-Cortés, Gemma Manich, Beatriz Almolda, Berta González, Margalida Coll-Andreu · FENS Forum 2024
Aims: Post-injury physical exercise can reduce memory deficits associated to traumatic brain injury (TBI) in late adolescent and young adult rats, but both the effectiveness of this treatment and possible sex-dependent effects in late middle-aged injured rats are important issues still unsolved. The aim of the present work was to examine whether chronic object recognition memory (ORM) deficits associated to TBI can be alleviated by post-injury physical exercise in males and females late middle-aged rats. Methods: 14 months-old rats were submitted to a controlled cortical impact injury model of
ePoster · Neuroscience