Topic: Natural history

SYNGAP1 Natural History Study/ Multidisciplinary Clinic at Children’s Hospital Colorado

Four questions about brain and behaviour

Tinbergen encouraged ethologists to address animal behaviour by answering four questions, covering physiology, adaptation, phylogeny, and development. This broad approach has implications for neuroscience and psychology, yet, questions about phylogeny are rarely considered in these fields. Here I describe how phylogeny can shed light on our understanding of brain structure and function. Further, I show that we now have or are developing the data and analytical methods necessary to study the natural history of the human mind.

Rare Disease Natural History Studies: Experience from the GNAO1 Natural History study in a pre and postpandemic world