Topic: NDNF

Cortex harbors a diverse range of inhibitory interneuron (IN) types, each of which shapes cortical activity in a unique way. Collectively, these INs control and orchestrate neuronal activity, thereby bestowing cortex with its computational power. Whereas genetic markers have greatly facilitated the study of various cortical IN types, a selective marker for INs in L1 has long been missing. Here, we use the recently identified neuron-derived neurotrophic factor (NDNF) to characterize the properties of mouse auditory cortex L1INs in vitro. First, using in vitro patch-clamp recordings in combinati