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Topic: network bursting

ePoster
1 ePoster

In Applied Mathematics and Bayesian Statistics

ePoster · Computational Neuroscience

Effective excitability: a determinant of the network bursting dynamics revealed by parameter invariance

Oleg Vinogradov, Emmanouil Giannakakis, Betül Uysal, Shlomo Ron, Eyal Weinreb, Holger Lerche, Elisha Moses, Anna Levina · Bernstein Conference 2024

Neuronal cultures in vitro are a versatile system for studying the basic properties of individual neurons and neuronal networks that recently gained additional attention as a precision medicine tool. Mature neuronal cultures exhibit synchronized collective dynamics called network bursting. This activity can provide insights into the network's cellular composition, network topology, or any underlying pathological processes. An effective method to investigate network bursting dynamics is to map it onto a simplified dynamical model, and then examine the model's dynamic regimes and the characteri