Structural and genetic determinants of zebrafish functional brain networks
Antoine Legare, Mado Lemieux, Vincent Boily, Sandrine Poulin, Arthur Legare, Patrick Desrosiers, Paul De Koninck · COSYNE 2025
Understanding the structural and functional network architectures of nervous systems has been a key focus of neuroscience. Many features of brain-wide neuronal networks have been identified in mammals using noninvasive methods that lack cellular information. Here, we performed whole-brain calcium imaging in zebrafish larvae to investigate the structural and genetic basis of functional connectivity (FC) at single-cell resolution. Neural activity from $\sim$50,000 neurons was recorded in head-restrained transgenic larvae expressing a pan-neuronal calcium sensor, while monitoring their tail movem
ePoster · Neuroscience