Topic: neurochemical cell groups

Cortical interneurons can be categorized into distinct subtypes based on multiple modalities; however, it remains unclear to what extent these modalities are correlated. In this study, we collected morphological, electrophysiological and molecular expression data in L5 interneurons of the mouse somatosensory cortex (S1) using Patch-PCR, aiming to reveal the correlations between molecular marker expressions and morpho-electric properties. An integrated classification procedure based on extracted morphological and electrophysiological features yielded 11 major morpho-electric subtypes (M/E types