Topic: NeuroDeblur

We developed a novel deconvolution software (NeuroDeblur), which significantly enhances the visibility of minute details, such as neurons or nerve fibres, in large image stacks captured by light-sheet, confocal, or bright-field microscopy. NeuroDeblur employs synthetic point spread functions tailored to each of these imaging modalities by utilizing a sophisticated optical model of the imaging procesess. Experimental point spread functions derived from recordings of fluorescent beads can be used additionally. The software features a sophisticated adaptive background removal algorithm and automa