Exploring the influence of distinct dentate gyrus interneuron subtypes on coping behavior
Adi Tenenhaus Zamir, Ma Chen, Rachel Anunu, Martin Kreibel, Hansjürgen Volkmer, Gal Richter-Levin · FENS Forum 2024
The dorsal dentate gyrus (dDG) plays a pivotal role in stress vulnerability and resilience. dDG granule cells interact with various interneuron subtypes, forming a complex local circuit essential for stress processing. Studies have shown differential activity in specific interneuron subtypes in response to stress, impacting coping mechanisms.This study examines the impact of two distinct categories of DG interneurons, chandelier and basket cells, on coping behavior. Ephrin A7 (EphA7) stabilizes synaptic terminals in basket cells, while Neurofascin (NF) facilitates axo-axonic synapse formation
ePoster · Neuroscience