Topic: neuronal adaptation

Burst-suppression (BS) is a highly structured electroencephalogram (EEG) pattern characterized by alternating periods of high-voltage activity (bursts) and low or flatline activity (suppression). In non-anesthetized adults, BS indicates severe brain pathology, e.g. due to oxygen and glucose deprivation [1]. There are two types of BS: one with identical bursts that are highly periodic and uniform in shape, often signaling a poor prognosis, and one without identical bursts [2]. The neuronal mechanisms behind BS and these variations remain largely unknown. Some studies suggest the involvement of