Topic: neuronal mitochondrial function

Altered functional connectivity in human brain networks has been reported in mood disorders. A moderating hub between resting state networks (RSNs) and the medial temporal lobe (MTL) is the parahippocampal cortex (PHC), where abnormal activity has been reported in depressed patients and suicide attempters. Alterations in neuronal mitochondrial function may contribute to depression and suicidal behavior, however, little is known about the underlying molecular level changes in relevant structures. Specifically, expressional changes related to suicide have not been reported in the PHC. Here, we c