Neuroprosthetic interventions for orthostatic hypotension in neurological diseases
Suje Amir, Remi Hudelle, Elaine Soriano, Lois Mahe, Nicolas Hankov, Leonie Asboth, Robin Demesmaeker, Viviana Aureli, Edouardo Martin-Moraud, Julien Bally, Quentin Barraud, Bernard Schneider, Erwan Bezard, Stephanie Lacour, Aaron Phillips, Jocelyne Bloch, Jordan Squair, Gregoire Courtine · FENS Forum 2024
Neurological diseases such as Multiple System Atrophy (MSA), Parkinson's disease, Lewy Body Dementia, and Pure Autonomic Failure lead to severe dysfunctions of the autonomic nervous system, resulting in neurogenic orthostatic hypotension. Current treatments remain limited, and certain therapies, such as dopamine replacement, may worsen symptoms. Our recent research revealed how a neuroprosthetic intervention such as epidural electrical stimulation (EES) of the thoracic spinal cord regulates blood pressure, leading to the development of a neuroprosthetic baroreflex effective across multiple spe
ePoster · Neuroscience