Topic: neurotransmitter exocytosis

The interplay of the calcium concentration and the anatomical structure at the presynaptic zone of presynaptic boutons is an important challenge of the relationship of form and function in (computational) neuroscience. A simple model system to study such basic effects is the neuromuscular junction of the Drosophila larva (NMJ). At this synapse, specific structures can be found. Its presynaptic boutons are larger than usual vertebrate synapses, also they bear several presynaptic zones. Different anatomic structures can be found at these zones. In part, they incorporate a so-called T-Bar, which,