Topic: noise clusters

The availability of high-density electrophysiology techniques is transforming systems neuroscience, enabling experimental labs to record activity from hundreds of neurons throughout the brain simultaneously. However, extracting single-cell activity from the resulting large datasets remains challenging, as various experimental conditions introduce sources of contaminating noise, and even optimized spike-sorting algorithms may produce false positive units. This requires labor-intensive manual evaluation of spike clusters.To address this challenge, we extended existing analyses and incorporated m