Revealing hidden targets in memory assemblies: The minimal engram for contextual memory encoding
Raquel Garcia Hernandez, Luis Álvarez-García, Alejandro Trouvé-Carpena, Hernan A. Makse, Santiago Canals · FENS Forum 2024
Memory mechanisms remain elusive in their system implementation. Previous research, combining fMRI and electrophysiology in anaesthetized rats, has shown that synaptic plasticity in the Dentate Gyrus (DG) orchestrates coordination in memory-related brain networks. By employing graph theory and pharmacogenetic tools, we further unveiled a hierarchy in system-level communication that highlighted interactions between the hippocampus, nucleus accumbens, and prefrontal cortex. However, whether a similar functional architecture supports brain coordination in awake behaving animals remains unknown.Us
ePoster · Neuroscience