Topic: novelty coding

The hippocampal formation is a crucial region in the encoding and retrieval of memory, thought to be mediated through ensemble formation and recruitment or intrinsic attractor dynamics. Additionally, it has been shown that overall hippocampal population activity reflects environmental novelty. However, a common neural basis supporting these two processes remains unknown. Furthermore, many memories contain overlapping features, and it remains to be established how specific memories are retrieved without interference in the hippocampus. We propose that both engram and attractor models hinge on l