Reduction of inter-individual variance in functional magnetic resonance imaging improves the prediction of individual pain ratings
Ole Goltermann, Christian Büchel · FENS Forum 2024
The promise of fMRI to detect robust inter-individual differences in health and behavioural outcomes and its potential use as a biomarker has been increasingly called into question. In a recent study (Hoeppli et al., 2022), the authors argued that, in the context of pain perception, fMRI was sensitive to small differences in applied noxious stimuli within an individual, but failed at predicting inter-individual differences. Here, we test in six studies whether this absent predictive power can be restored by accounting for inter-individual variance and the use of clearly distinguishable experim
ePoster · Neuroscience