Hypothalamic-thalamic pathways enable leptin to regulate social and sexual behaviours
Anne Petzold, Rebecca Figge-Schlensok, Chantal Wissing, Deema Awad, Hanna van den Munkhof, Tatiana Korotkova · FENS Forum 2024
Mammalian reproduction is highly energy intensive, and requires an animal to prioritize feeding or sociosexual interaction, depending on need and opportunity. We have recently shown that two leptin-sensitive populations – leptin receptor-expressing (LepRLH) and neurotensin-expressing (NtsLH) neurons of the lateral hypothalamus – act in a complementary manner to enable resistance to hunger and gate the pursuit of social needs (Petzold et al., Cell Metab 2023).Currently, using single-cell Ca2+ imaging in freely moving mice, we found that LepRLH neurons not only preferentially encoded conspecific
ePoster · Neuroscience