Topic: Nucleus of the Optic Tract (NOT)

The role of sensory systems is to interpret real-world events to facilitate behavior. For instance, the visual system enacts compensatory eye movements based on a global motion representation, generated by combining local motion signals from the retina. However, due to the aperture problem, local motion signals are inherently ambiguous, and how the visual system solves the aperture problem is unclear. We studied how the mouse Nucleus of the Optic Tract (NOT) integrates retinal visual information and how this supports behavioral responses. NOT mediates the horizontal optokinetic reflex, the com