Associations between maternal pre-pregnancy BMI and white matter integrity in infants
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari · FENS Forum 2024
Emerging evidence suggests that intrauterine exposures to maternal factors such as to maternal pre-pregnancy body mass index (MBMI) impacts the neurodevelopment of the offspring in a region-specific way, possibly contributing to future obesity risk of the offspring. Our study investigates the associations between MBMI and neonatal global white matter integrity in 157 infant-mother dyads from FinnBrain Birth Cohort Study (www.finnbrain.fi). Following TBSS (Tract-based Spatial Statistics) skeletonization, associations between MBMI and mean diffusivity values were assessed using a voxel-wise non-
ePoster · Neuroscience