40 Hz gamma visual stimulation restores brain dynamics and boosts memory in a new mouse model of early Alzheimer’s disease
Matthieu Aguilera, Chantal Mathis, Demian Battaglia, Romain Goutagny · FENS Forum 2024
Alzheimer’s disease (AD) is a neurodegenerative disease and the world leading cause of dementia, yet still no effective treatments are available. Recently, a non-invasive therapy based on 40 Hz gamma stimulation using sensory stimuli (GENUS) showed beneficial effects on memory performances in several AD mouse models and mild probable AD patients. However, mechanisms underlying these positive effects, such as amyloid plaque clearance, microglial activation or gamma rhythm restauration, are still matter of intense debate. Here, we test the alternative hypothesis that GENUS might rescue memory de
ePoster · Neuroscience