ePoster · Neuroscience
Lateral entorhinal cortex modulation of spatial and object-firing in the medial entorhinal cortex
Brianna Vandrey, Alyssa Meng, Matthew Nolan · FENS Forum 2024
Standard models of episodic memory emphasise that parallel streams of spatial information, arriving from medial entorhinal cortex (MEC), and object information, arriving from lateral entorhinal cortex (LEC), are integrated within the hippocampus. However, we recently discovered that fan cells in the LEC send direct projections to MEC, suggesting that spatial and object information could be integrated within MEC (Vandrey et al. 2022, doi:10.7554/eLife.83008). Evidence for object-related firing in the MEC is consistent with this possibility, but whether LEC projections influence spatial and obje