Characterization of cell type distribution and development of mouse area centralis
Diana Petre, Daria Madan, Mălina Barbu, Ana-Maria Sisman (Taranciuc), Elangovan Boobalan, Brian Brooks, Tudor Constantin Badea · FENS Forum 2024
Retinal Ganglion Cell (RGCs) number density is a key feature of retinal specialization for high visual acuity, as seen in retinal foveas or area centralis (ArCe) in mammals. Mice are broadly used as a genetically tractable model of mamalian vision, however no region of high visual acuity was known. Using combinatorial genetics in Brn3cCre; Brn3bCKOAP mice our group previously reported a region of high RGC density, oriented in a temporo-nasal fashion. We report now experiments characterizing ArCe cell types and developmental features. Using sparse AAVFLEXeGFP virus infections in Brn3cCre; Brn3b
ePoster · Neuroscience