Topic: olivo-cerebellar system

The inferior olive (IO) is an evolutionary conserved brain region important for motor learning. As part of the olivo-cerebellar system (OCS), the IO sends climbing fiber projections to the Purkinje neurons (PN) and generates complex spikes. Despite its significance, the mechanisms guiding IO responses to sensory inputs for complex spike generation are unclear. This project aims to uncover how IO neurons integrate sensory input, impacting cerebellar control of movement.Focusing on IO afferents from the superior colliculus (SC), crucial for orienting behavior, we identified a novel target area f