Mind the gradient: context-dependent selectivity to natural images in the retina revealed with a novel perturbative approach
Matías Goldin,Alexander Ecker,Baptiste Lefebvre,Samuele Virgili,Thierry Mora,Ulisse Ferrari,Olivier Marre · COSYNE 2022
Fri, Mar 18, 2022
Understanding how sensory neurons extract relevant information from natural scenes is a major challenge in neuroscience. Probing sensory systems with simple stimuli give limited insights on natural scene processing, and probing selectivity during natural scene stimulation is difficult. Even in the retina, is not clear how Retinal ganglion cells (RGC) extract specific features from natural scenes and send this information to the brain. Many studies using simple, artificial stimuli have shown responses to local light increase (ON-responses), and/or decrease (OFF), but it is unclear if this selec