Oxygen in motion: Anxiety-related changes in oxygen levels within the ventral hippocampus of rats
Zoi Balla, Patrizia Voehringer, Andreas Johann Genewsky, Carsten Wotjak · FENS Forum 2024
The ventral hippocampus has emerged as a central hub for the orchestration of negative effects. We employed wireless amperometric O2 measurements in freely moving rats as a surrogate readout for changes in neuronal activity with translational value for fMRI studies in humans. From the Research Domain Criteria (RDoC) matrix, here, mainly one branch, namely the negative valence system is addressed using a modified Elevated Plus-Maze, male Wistar rats are tested under controllable (modified Elevated T-Maze, mETM with free exploration of one open and two closed arms) and uncontrollable (Open Arm C
ePoster · Neuroscience