Thermoregulatory GABAergic vlPOA neurons induce neuroprotection after stroke via a hypothalamic pathway
Buse Balaban, Aysenur Ozpinar, Dilsiz Pelin, Serdar Altunay, Saltuk Bugra Baltaci, Halil Ibrahim Koc, Caglar Beker, Ertugrul Kilic · FENS Forum 2024
Stroke is a preeminent contributor of the global burden of diseases. Hypothermia, among other therapeutic approaches, has been proposed to promote neural survival after stroke, yet the physiological cooling remains ineffective and induces collateral side effects. The thermoregulatory mechanisms are under the control of neuronal identities that connect peripheral signals of the central nervous system, which are predominantly conveyed into the hypothalamus. Here, we aimed to identify a thermoregulatory neuronal subpopulation located at the dorsomedial hypothalamus (DMH) and investigate the DMH-p
ePoster · Neuroscience