Topic: optogenetic response dynamics

Optogenetic stimulation has recently proven effective in partially restoring vision in the human eye, underlining its potential in clinical applications. Using this technique in sensory cortices could leverage the spatial organization of stimulus feature encoding across the cortical surface to artificially induce perception and restore a lost sense. However, achieving precise stimulation to recruit sensory neuronal populations is challenging, as the full spatial extent of neuronal morphology, including distal parts, may contribute to optogenetic activation. In this study, we investigate how mo