Topic: orexin transmission

Numerous studies have demonstrated the correspondence between orexin transmission and reward-related behaviors. Orexin receptors are expressed in the hippocampus regions such as CA1, CA2, and CA3, as well as the DG region. The hippocampus is essential in learning and memory, and there is a correlation between reward and learning and memory processing. The dentate gyrus (DG) is the main gateway of the hippocampal formation, receives and integrates inputs from the rest of the hippocampus formation and regulates addiction-related behaviors. Methamphetamine and other psychostimulants can produce a