A PACAP-glutamate-ACh pathway from a novel neuronal subpopulation in PB/KF innervates CeC PKCδ cells with calyceal terminal forming Gray I and II axosomatic synapses
Limei Zhang, Vito S. Hernandez, Sunny Z. Jiang, Lee E. Eiden · FENS Forum 2024
Using immuno-electron microscopic methods (FIBSEM-TEM) we have previously reported PACAPergic calyceal axon terminals in the ventro-lateral capsular subdivision of the central amygdala (FENS abstract 2020, 2022) in rat. To further investigate the origin and molecular constituents of these peculiar calyceal terminals, we used fluorogold retrograde and AAV5-EF1a-DIO-hChR2(H134R)-eYFP anterograde tracing in Adcyap1-2A-cre mice and investigated its molecular signature for both presynaptic and postsynaptic components. We report here that this Calyx of Held-like giant synapse terminal has mixed glut
ePoster · Neuroscience