Topic: pallidostriatal feedback loops

An increase in beta-band frequency (13-30 Hz) activity has been observed in different nuclei of the basal ganglia (BG) of patients with Parkinson's disease (PD). However, recent studies have shown that beta oscillations are not only specific to pathological conditions. They have been shown to occur during sensorimotor tasks in healthy subjects. In this study, we used both a rate model and a spiking neural network to investigate the mechanisms responsible for the generations of beta oscillations. Results show that using a rate model with realistic time constants, the classical candidate - a rec